Molecular AND-logic for dually controlled activation of a DNA-binding spiropyran.
نویسندگان
چکیده
A spiropyran photoswitch is activated using UV light and protons from a form that shows no interaction with DNA to a form that binds to DNA by intercalation. This scheme is interpreted as a biologically relevant logic AND gate with potential applications as a dually controlled anticancer drug.
منابع مشابه
Molecular AND-logic for dually controlled activation of a DNA-binding spiropyranw
Molecular logic has traditionally been used in the mimicry of the functions performed by silicon-based electronic devices. Here, cleverly designed decision-making molecules deliver a binary on (1)–off (0) response upon exposure to stimuli such as ions, voltage, and light, according to the respective logic scheme. The entire set of two-input logic gates has been mimicked on the molecular scale, ...
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 38 شماره
صفحات -
تاریخ انتشار 2010